Here is the latest highway information courtesy of VicRoads
Melbourne to Adelaide - Western Highway now open [UPDATE 4:20pm Will be closed after 5pm until further notice. Alernative route Princes Hwy to Geelong, Hamilton Hwy-Glenelg Highway to Mt Gambier.]
Melbourne to Mildura - Sunraysia Highway now open
The Murray Valley Highway is open however under threat at Kerang and Echuca townships and should be avoided.
Princes Highway - Closed at McKinnons Bridge Noorat Road. Detour via Camperdown-Cobden Road and Warrnambool-Cobden Road.
This information current to 4:24pm 17/1/11